Retin A vs Cell Growth Factors- Which is Better?

This week’s question  shows how far  skin care products  have come in the last ten years.  Both cell growth factors and Retin A  are significant anti-aging tools.  Cell growth factors wake up old tired fibroblasts in the skin and get them to provide  more collagen.  Retin A also  increases healthy young collagen in the skin but we don’t exactly know  why.  In addition the retinoids stimulat circulation   producing a youthful healthy glow to the skin.  Finally retionoids  exfoliate the skin  that has three, count ’em three great benefits–  it removes dull dry tired skin, it stimulates the growth of  new fresh  skin and it slowly lightens discolorations and flat age spots. Nice.

But both retinoids and cell growth factors products have a few  issues.  Retinoids  can be very irritating and  some women  just can’t use them.  For women of color, retin A  may actually cause increased  pigmentation because of the irritation.  Cell growth factors are far more gentle and do not increased sensitivity to the sun like Retin A and alpha hydroxy acids. In cold wintery weather it can be very hard to use Retin A everyday and cell growth factors will   help the skin withstand cold windy weather.  However  they are unregulated. Unlike retinoids which have to list their concentration, there is little way of knowing how much  growth factor is actually  in a  that pricy tube or jar.  It could be a full effective dose or  just a drop  so that  it can be included on the list of ingredients on the label.

To bottomline it,  I don’t think its an either/or situation.  I think there is a role for both retinoids and cell growth factors  in a  successful  anti-aging plan.  There is good science behind  Rejuve MD with cell growth factors  and I use it rotation with Retin A Micro and a vitamin C serum  from Skinceuticals.   I tend to reach for my cell growth factors when  I don’t want to wait for 30 minutes to apply a night treatment before going to  bed.  Both  Retin A and vitamin C can sting  if applied to freshly washed skin and treatment products with cell growth factors are soothing rather than irritating.    One final thought. Some experts recommend using both at at the same time.  I’m not a big fan of layering because I’m concerned about absorption .  I use them on different nights and love the results.

6 thoughts on “Retin A vs Cell Growth Factors- Which is Better?

  1. I use retin A and have for a long time. I am 55 and have some broken capillaries
    on my checks, I received a Clarisonic as a gift. My question is will the clarisonic
    make the capillaries worse and should I use it.

  2. I am currently using a vitamin C serum from Cosmetic Skin Solutions. I am very satisfied with it over traditional vitamin C’s such as Skinceuticals.

  3. I now use my AHA cream every day, under the eyes also,it is safe in pregnancy. Studies claim that AHA unblocks pores, keep them clear, so it helps in keeping acne under control, but…also as a bonus, after a long use, diminish wrinkles.

  4. I tried both Retin A and Rejuve MD. The Retin A gave me little results but Rejuve MD was a disaster ! Looking at the ingredient list, the active ingredients came at the very end. In addition, after asking some biologist, they all laughed when I mentioned to them Bio-identical growth factors. They said there are no such thing. There are bio-identical hormones but not growth factors. There is no doubt growth factors are great for our skin and I am now using one that is wonderful but you will need to get the right legit growth factor product and not Rejuve MD. Dermatologist are using their names to generate another income. I will never use any products developed by derm doctors. This story is been over done.

    • I’m not a big fan of bio-identical hormones and there is a wide range of value in growth factors. I still believe (and most honest dermatologists agree with me) that Retin A is the gold standard for anti-aging skin care. I think that growth factor based products may be helpful when someone can’t tolorate Retin A or in addition to Retin A. I’m sorry you had such a bad experience with Rejuve MD and I hope you were able to get a refund.

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